Officers with the Ottawa County Sheriff's Office were dispatched to reports of a crash on 112th Avenue and Stanton Street.
When they arrived on scene, a 48-year-old from Grand Haven, whose name has not yet been released, was found unresponsive and died at the scene.
The other driver, a 20-year-old male from Hudsonville and their 24-year-old female passenger were transported to the hospital in stable condition with no life-threatening injuries.
Investigation into the crash remains ongoing.