The rules of the "Town Hall" style debate were clear. No applause, no cheering, no booing. The audience was to remain silent. And no matter how often Anderson Cooper and Martha Radditz reminded the audience of this, occasionally, a few outbursts came through.
Here were some of the biggest reactions:
Both candidates were interrupted constantly to keep time. Trump was more vocal about the practice than Clinton
And then this guy gave the most mic-dropping question of all time: